We all understand the absurdity of that old adage “sleep is for the weak”. That attitude has been put to rest by a bevy of studies empirically showing that sleep in fact makes you smarter, stronger, and more creative. But when it comes to extended rest and relaxation, there still exists a sort of taboo.

I recently got back from a five day holiday vacation to the Puerto Rican island of Culebra, planned last minute because I felt dangerously close to burning out. Every time I talked to anyone about the trip, I included the disclaimer “it’s only my third break since Amicus was founded”. Every time. It was only once I was lying on a beach that I realized what I was doing: I was making excuses for taking a break because I felt guilty. To my teammates, to my friends, to fellow entrepreneurs. I might as well have been saying “vacations are for the weak”.

Professional runners take long breaks...

For the first time, I’m excited about what’s happening in the world of entertainment. In an industry that has long resisted the sort of disruption technology has brought to other fields, 2013 is starting to look like an inflection point.

Just last night, an Internet company (Netflix) won three Emmy awards. And while the top prize went to a show from a more traditional network, the producer of that show credited Netflix for its success during his acceptance speech. An industry that has long resisted disruption from the tech world instead lauded an Internet company on stage, and offered it their most prized honor.

Last week, a video game (Grand Theft Auto V) reached $1B in sales in just three days. It achieved that milestone faster than any movie, any album, any book. A piece of programmable content is now the fastest growing entertainment property in history.

And at Sundance this year,...

We all know that exercise is good for one’s brain and body. The benefits are well documented. That didn’t stop me from making a decision many entrepreneurs make – I decided I no longer had time for it after starting Amicus. In the time it would take to head to the gym, I could get through a dozen emails, mockup a new feature, or talk to some customers. So I spent more time working and less time working out.

Soon I was having trouble dealing with the stress of Amicus’ ups and downs. I had trouble sleeping and even started snapping at my teammates. It got bad enough that I turned to mentors for advice on what to do. I was surprised by the feedback I kept hearing: “exercise more”. So I started irregularly hitting the gym. I didn’t make a real lifestyle change, however, until Amicus got accepted into Y Combinator last year.

Our first day of YC, PG stood up in front of the batch and said:

“We can still learn from history the invaluable lesson that an enormously powerful and profitable evil can be overcome.”

–David Brion Davis

Entrepreneurs have an inherent distaste for entrenchment, and seek to disrupt it wherever it exists. Because of the history of Silicon Valley, entrepreneurs are typically focused on market entrenchment. The organizations being disrupted are market goliaths – the Microsofts, IBMs, and Oracles – that use their connections, capital, and incumbency to stifle innovation. In our world, those that bring about this disruption are heralded as innovators and held up as exemplars.

It’s time we expanded our field of vision. There is another category of powerful entrenched interests in our midsts – another flavor of anachronistic goliath. These kind don’t look to protect their market caps or their cash flows; they look to protect their influence and their...